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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Asparaginyl-tRNA synthetase

UniprotKB/SwissProt ID: Q96I59 (Q96I59)

Gene Name: NARS2

Organism: Homo sapiens (Human)

Function: Mitochondrial aminoacyl-tRNA synthetase that catalyzes the specific attachment of the asparagine amino acid (aa) to the homologous transfer RNA (tRNA), further participating in protein synthesis (PubMed:25385316). The reaction occurs in a two steps: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn) (Probable)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix. Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004364 Aa-tRNA-synt_II
IPR006195 aa-tRNA-synth_II
IPR045864 aa-tRNA-synth_II/BPL/LPL
IPR004522 Asn-tRNA-ligase
IPR002312 Asp/Asn-tRNA-synth_IIb
IPR012340 NA-bd_OB-fold
IPR004365 NA-bd_OB_tRNA

The S-nitrosylation sites of Q96I59

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 475 VIPFPRFPHS C LL--------