Protein Name:
Methylthioribulose-1-phosphate dehydratase
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UniprotKB/SwissProt ID: Q96GX9 (Q96GX9)
Gene Name:
APIP
Organism: Homo sapiens (Human)
Function: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96GX9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
188 |
AHAMNEYPDS C AVLVRRHGVY |
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| 2 |
76 |
ERIQPEDMFV C DINEKDISGP |
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| 3 |
97 |
SPSKKLKKSQ C TPLFMNAYTM |
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