Protein Name:
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like
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UniprotKB/SwissProt ID: Q96G46 (Q96G46)
Gene Name:
DUS3L
Organism: Homo sapiens (Human)
Function: Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs) (PubMed:34556860). Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs (PubMed:34556860). Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation (PubMed:34556860)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96G46
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
124 |
KPTNYDKNRL C PSLIQESAAK |
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| 2 |
162 |
ETKPADLGPR C VLFETFGRCP |
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| 3 |
171 |
RCVLFETFGR C PYGVTCRFAG |
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| 4 |
282 |
STPPSSPVRT C GPLTDEDVVR |
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| 5 |
296 |
TDEDVVRLRP C EKKRLDIRGK |
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| 6 |
315 |
GKLYLAPLTT C GNLPFRRICK |
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| 7 |
377 |
EGAFPDTMTK C AELLSRTVEV |
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| 8 |
396 |
EVDFVDINVG C PIDLVYKKGG |
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| 9 |
408 |
IDLVYKKGGG C ALMNRSTKFQ |
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