Protein Name:
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
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UniprotKB/SwissProt ID: Q96FE5 (Q96FE5)
Gene Name:
LINGO1
Organism: Homo sapiens (Human)
Function: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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