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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: U5 small nuclear ribonucleoprotein 40 kDa protein

UniprotKB/SwissProt ID: Q96DI7 (Q96DI7)

Gene Name: SNRNP40

Organism: Homo sapiens (Human)

Function: Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:29301961, PubMed:29360106, PubMed:30315277, PubMed:30705154). Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome (PubMed:16723661, PubMed:26912367, PubMed:9774689). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020472 G-protein_beta_WD-40_rep
IPR052234 U5_snRNP_Component
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of Q96DI7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 157 LKGHTSFVNS C YPARRGPQLV   
2 168 YPARRGPQLV C TGSDDGTVKL   
3 291 VHNFEKNLLR C SWSPDGSKIA