Protein Name:
FXYD domain-containing ion transport regulator 5
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UniprotKB/SwissProt ID: Q96DB9 (Q96DB9)
Gene Name:
FXYD5
Organism: Homo sapiens (Human)
Function: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (By similarity). May increase NKA activity by increasing the apparent affinity for Na(+) (PubMed:18263667). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (PubMed:11756660)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Basolateral cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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