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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1

UniprotKB/SwissProt ID: Q96BK5 (Q96BK5)

Gene Name: PINX1

Organism: Homo sapiens (Human)

Function: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000467 G_patch_dom
IPR050656 PINX1

The S-nitrosylation sites of Q96BK5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 265 APAEEQLRGP C WDQSSKASAQ