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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Leucine-rich repeat-containing protein 59

UniprotKB/SwissProt ID: Q96AG4 (Q96AG4)

Gene Name: LRRC59

Organism: Homo sapiens (Human)

Function: Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Microsome membrane. Endoplasmic reticulum membrane. Nucleus envelope

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR050216 LRR_domain-containing

The S-nitrosylation sites of Q96AG4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 131 DPVLAKVAGD C LDEKQCKQCA  CCCCCCCCCC H HHCCCCCEEC  5.16% 19483679
2 48 LPKATILDLS C NKLTTLPSDF  CCCCCCCCCC H HHCCCCCEEC  7.28% 19483679
2212679
3 59 NKLTTLPSDF C GLTHLVKLDL  CCCCCCCCCC H HHCCCCCEEC  5.39% 19483679