Protein Name:
Protein FAM162A
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UniprotKB/SwissProt ID: Q96A26 (Q96A26)
Gene Name:
FAM162A
Organism: Homo sapiens (Human)
Function: Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues (PubMed:15082785). May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition (PubMed:15082785). May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion membrane
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Graphical Visualization of S-nitrosylation Sites:
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