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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Alcohol dehydrogenase class-3

UniprotKB/SwissProt ID: Q96533 (Q96533)

Gene Name: ADH2

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Alcohol dehydrogenase catalyzing the reduction of nitrosoglutathione (PubMed:38308388). Can also use long-chain alcohols including cinnamyl alcohol and geraniol, and, to a lower extent, octanol (PubMed:38308388). Plays a central role in formaldehyde detoxification (PubMed:12913179). Not able to use ethanol (EtOH) as substrate (PubMed:38308388)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013149 ADH-like_C
IPR013154 ADH-like_N
IPR014183 ADH_3
IPR002328 ADH_Zn_CS
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf

The S-nitrosylation sites of Q96533

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 370 KAFDLLHEGT C LRCVLDTSK-