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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: T-complex protein 1 subunit theta

UniprotKB/SwissProt ID: Q94K05 (Q94K05)

Gene Name: CCT8

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Contributes to stem cell maintenance through its impact on transcription factors trafficking through plasmodesmata (PubMed:21868675). Probably involved in refolding translocated, partially unfolded proteins, including viral movement proteins (PubMed:21868675, PubMed:22476462)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR012721 Chap_CCT_theta
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/GroEL/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf

The S-nitrosylation sites of Q94K05

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 219 KLLGGGLHNS C IVRGMVLKSD   
2 490 KLGIDLEEGA C KDVSETKVWD   
3 517 FALKYASDAA C TVLRVDQIIM