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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 3-isopropylmalate dehydratase large subunit, chloroplastic

UniprotKB/SwissProt ID: Q94AR8 (Q94AR8)

Gene Name: IIL1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (PubMed:19150812, PubMed:20663849). Functions in both the biosynthesis of leucine and in the methionine chain elongation pathway of aliphatic glucosinolate formation (PubMed:19597944)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Plastid, chloroplast stroma

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015931 Acnase/IPM_dHydase_lsu_aba_1/3
IPR001030 Acoase/IPM_deHydtase_lsu_aba
IPR036008 Aconitase_4Fe-4S_dom
IPR006251 Homoacnase/IPMdehydase_lsu
IPR050067 IPM_dehydratase_rel_enz
IPR033941 IPMI_cat

The S-nitrosylation sites of Q94AR8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 376 VKIDRVYIGS C TGGKTEDFMA  CCCCCCCCCC C CCCCCCCCCC  3.27% 22115780
2 465 TYARLNEPQV C VSTTNRNFPG  CCCCCCCCCC C CCCCCCCCCC  1.36%