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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein TOPLESS

UniprotKB/SwissProt ID: Q94AI7 (Q94AI7)

Gene Name: TPL

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Transcriptional corepressor. May repress the expression of root-promoting genes in the top half of the embryo to allow proper differentiation of the shoot pole during the transition stage of embryogenesis. Regulates the expression of PLT1 and PLT2. Negative regulator of jasmonate responses. Negative regulator of auxin responses. Negative regulator of multiple floral organ identity genes (PubMed:23034631). Required for ovule development (PubMed:25378179)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006595 CTLH_C
IPR006594 LisH
IPR027728 Topless_fam
IPR048419 Topless_Znf
IPR054532 TPL_SMU1_LisH-like
IPR054080 TPR1-like_2nd
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of Q94AI7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 204 DIKTLFVDHS C GPPNGARAPS   
2 757 KLTEVSEPSQ C RSLRLPENLR