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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Transcription factor IIIB 90 kDa subunit

UniprotKB/SwissProt ID: Q92994 (Q92994)

Gene Name: BRF1

Organism: Homo sapiens (Human)

Function: General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011665 BRF1_TBP-bd_dom
IPR013763 Cyclin-like_dom
IPR036915 Cyclin-like_sf
IPR000812 TFIIB
IPR013150 TFIIB_cyclin
IPR013137 Znf_TFIIB

The S-nitrosylation sites of Q92994

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 289 EFMKIDLEEE C DPPSYTAGQR