Protein Name:
Peroxisomal membrane protein PEX13
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UniprotKB/SwissProt ID: Q92968 (Q92968)
Gene Name:
PEX13
Organism: Homo sapiens (Human)
Function: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (PubMed:28765278, PubMed:8858165, PubMed:9653144). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (PubMed:28765278, PubMed:8858165, PubMed:9653144). Involved in the import of PTS1- and PTS2-type containing proteins (PubMed:8858165, PubMed:9653144)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Peroxisome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q92968
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
220 |
LWAESEGTVA C LGAEDRAATS |
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