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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glutaryl-CoA dehydrogenase, mitochondrial

UniprotKB/SwissProt ID: Q92947 (Q92947)

Gene Name: GCDH

Organism: Homo sapiens (Human)

Function: Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006089 Acyl-CoA_DH_CS
IPR006091 Acyl-CoA_Oxase/DH_mid-dom
IPR046373 Acyl-CoA_Oxase/DH_mid-dom_sf
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR013786 AcylCoA_DH/ox_N
IPR037069 AcylCoA_DH/ox_N_sf
IPR009100 AcylCoA_DH/oxidase_NM_dom_sf
IPR052033 Glutaryl-CoA_DH_mitochondrial

The S-nitrosylation sites of Q92947

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 176 PQLAKGELLG C FGLTEPNSGS   
2 289 GASSLGGPFG C LNNARYGIAW   
3 75 ILIRDTFRTY C QERLMPRILL