Protein Name:
Far upstream element-binding protein 2
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UniprotKB/SwissProt ID: Q92945 (Q92945)
Gene Name:
KHSRP
Organism: Homo sapiens (Human)
Function: Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q92945
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
176 |
QINKIQQDSG C KVQISPDSGG |
CCCCCCCCCC C CCCCCCCCCC |
4.52% |
20140087
19483679
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| 2 |
296 |
IGDPYKVQQA C EMVMDILRER |
CCCCCCCCCC C CCCCCCCCCC |
2.77% |
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| 3 |
436 |
EMTFSIPTHK C GLVIGRGGEN |
CCCCCCCCCC C CCCCCCCCCC |
3.85% |
20140087
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