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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

UniprotKB/SwissProt ID: Q92925 (Q92925)

Gene Name: SMARCD2

Organism: Homo sapiens (Human)

Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:22952240, PubMed:26601204). Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation (PubMed:28369036)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR030090 SMARCD2_SWIB_dom
IPR019835 SWIB_domain
IPR036885 SWIB_MDM2_dom_sf
IPR003121 SWIB_MDM2_domain

The S-nitrosylation sites of Q92925

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 355 QDGHEREYIN C NRYFRQIFSC   
2 365 CNRYFRQIFS C GRLRFSEIPM