Protein Name:
Ras-responsive element-binding protein 1
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UniprotKB/SwissProt ID: Q92766 (Q92766)
Gene Name:
RREB1
Organism: Homo sapiens (Human)
Function: Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters (PubMed:10390538, PubMed:15067362, PubMed:17550981, PubMed:8816445, PubMed:9305772). Represses the angiotensinogen gene (PubMed:15067362). Negatively regulates the transcriptional activity of AR (PubMed:17550981). Potentiates the transcriptional activity of NEUROD1 (PubMed:12482979). Promotes brown adipocyte differentiation (By similarity). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (PubMed:8816445)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus speckle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q92766
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
68 |
ETKEEKSSYN C PLCEKICTTQ |
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| 2 |
755 |
VDAFCAPDTV C RLCGEDLKHY |
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| 3 |
850 |
EASGRGEDSG C AALGDCKPLT |
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