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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nonsense-mediated mRNA decay factor SMG7

UniprotKB/SwissProt ID: Q92540 (Q92540)

Gene Name: SMG7

Organism: Homo sapiens (Human)

Function: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR018834 DNA/RNA-bd_Est1-type
IPR019458 Est1-like_N
IPR045153 Est1/Ebs1-like
IPR011990 TPR-like_helical_dom_sf

The S-nitrosylation sites of Q92540

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 537 LSTSRNLSNN C DTGEKPVVTF