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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

UniprotKB/SwissProt ID: Q923Z3 (Q923Z3)

Gene Name: Mto1

Organism: Mus musculus (Mouse)

Function: Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036188 FAD/NAD-bd_sf
IPR049312 GIDA_C_N
IPR004416 MnmG
IPR002218 MnmG-rel
IPR020595 MnmG-rel_CS
IPR026904 MnmG_C
IPR047001 MnmG_C_subdom
IPR044920 MnmG_C_subdom_sf
IPR040131 MnmG_N

The S-nitrosylation sites of Q923Z3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 103 DALDGLCSRI C DQSGIHYKVL