Protein Name:
Protein disulfide-isomerase A6
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UniprotKB/SwissProt ID: Q922R8 (Q922R8)
Gene Name:
Pdia6
Organism: Mus musculus (Mouse)
Function: May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:24508390). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (By similarity). May also regulate the UPR via the EIF2AK3 UPR sensor (By similarity). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum lumen. Cell membrane. Melanosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q922R8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
291 |
IINEDIAKKT C EEHQLCVVAV |
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