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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Fatty acyl-CoA reductase 1

UniprotKB/SwissProt ID: Q922J9 (Q922J9)

Gene Name: Far1

Organism: Mus musculus (Mouse)

Function: Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols (PubMed:15220348, PubMed:15220349). It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols (By similarity). In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis (PubMed:15220349)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR026055 FAR
IPR033640 FAR_C
IPR013120 Far_NAD-bd
IPR036291 NAD(P)-bd_dom_sf