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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ethanolamine-phosphate cytidylyltransferase

UniprotKB/SwissProt ID: Q922E4 (Q922E4)

Gene Name: Pcyt2

Organism: Mus musculus (Mouse)

Function: Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway (PubMed:17325045). Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis (PubMed:17325045)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR041723 CCT
IPR004821 Cyt_trans-like
IPR044608 Ect1/PCYT2
IPR014729 Rossmann-like_a/b/a_fold

The S-nitrosylation sites of Q922E4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 324 LLNHFKVDLV C HGKTEIVPDR  CCCCCCCCHH H CCCCCCCCCC  4.56% 21278135