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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: V-type proton ATPase 116 kDa subunit a 4

UniprotKB/SwissProt ID: Q920R6 (Q920R6)

Gene Name: Atp6v0a4

Organism: Mus musculus (Mouse)

Function: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Involved in normal vectorial acid transport into the urine by the kidney (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Apical cell membrane. Basolateral cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka

The S-nitrosylation sites of Q920R6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 249 CDGFRATIYP C PEHAAERREM