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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF2

UniprotKB/SwissProt ID: Q920G2 (Q920G2)

Gene Name: Nherf2

Organism: Rattus norvegicus (Rat)

Function: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endomembrane system. Nucleus. Apical cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015098 EBP50_C
IPR051067 NHER
IPR017300 NHERF-1/NHERF-2
IPR001478 PDZ
IPR036034 PDZ_sf