Protein Name:
Protein THEMIS2
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UniprotKB/SwissProt ID: Q91YX0 (Q91YX0)
Gene Name:
Themis2
Organism: Mus musculus (Mouse)
Function: May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production (PubMed:20644716). Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (PubMed:27992403)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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