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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Arsenite methyltransferase

UniprotKB/SwissProt ID: Q91WU5 (Q91WU5)

Gene Name: As3mt

Organism: Mus musculus (Mouse)

Function: Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR026669 Arsenite_MeTrfase-like
IPR025714 Methyltranfer_dom
IPR029063 SAM-dependent_MTases_sf

The S-nitrosylation sites of Q91WU5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 33 KTSADLQTNA C VTRAKPVPSY  CCCCCCHHHH H HHHHHHHHCH  3.31% 21278135