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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ribonuclease inhibitor

UniprotKB/SwissProt ID: Q91VI7 (Q91VI7)

Gene Name: Rnh1

Organism: Mus musculus (Mouse)

Function: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress. Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR041302 LRR_RI_cap
IPR050637 NLRP_innate_immun_reg

The S-nitrosylation sites of Q91VI7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 129 PMGDAGLKLL C EGLQDPQCRL  CCCCCCCCCC C CCCHHHHHHH  5.89%
2 147 CRLEKLQLEY C NLTATSCEPL  CCCCCCCCCC C CCCHHHHHHH  2.16%
3 186 DLHEPGVRIL C QGLKDSACQL  CCCCCCCCCC C CCCHHHHHHH  2.54%
4 194 ILCQGLKDSA C QLESLKLENC  CCCCCCCCCC C CCCHHHHHHH  5.7%
5 204 CQLESLKLEN C GITAANCKDL  CCCCCCCCCC C CCCHHHHHHH  2.81%
6 215 GITAANCKDL C DVVASKASLQ  CCCCCCCCCC C CCCHHHHHHH  5.53%
7 243 KLGNAGIAAL C PGLLLPSCKL  CCCCCCCCCC C CCCHHHHHHH  1.84%
8 251 ALCPGLLLPS C KLRTLWLWEC  CCCCCCCCCC C CCCHHHHHHH  4.55%
9 300 ELKDEGARLL C ESLLEPGCQL  CCCCCCCCCC C CCCHHHHHHH  3.85%
10 33 QQYEVVRLDD C GLTEVRCKDI  CCCCCCCCCC C CCCHHHHHHH  4.86% 21278135
11 357 PLGDEGVQEL C KALSQPDTVL  CCCCCCCCCC C CCCHHHHHHH  2.08%
12 404 SLRELDLSNN C MGGPGVLQLL  CCCCCCCCCC C CCCHHHHHHH  2.91% 19483679
13 80 LVLQGLQNPT C KIQKLSLQNC  CCCCCCCCCC C CCCHHHHHHH  3.74% 19483679
14 90 CKIQKLSLQN C GLTEAGCGIL  CCCCCCCCCC C CCCHHHHHHH  2.81%