Protein Name:
Protein MEMO1
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UniprotKB/SwissProt ID: Q91VH6 (Q91VH6)
Gene Name:
Memo1
Organism: Mus musculus (Mouse)
Function: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q91VH6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
55 |
IIAPHAGYTY C GSCAAHAYKQ |
CCCCEEEECC C CCCCEEECCC |
2.2% |
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| 2 |
58 |
PHAGYTYCGS C AAHAYKQVDP |
CCCCEEEECC C CCCCEEECCC |
2.05% |
20925432
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| 3 |
88 |
GPSHHVPLSR C ALSSVDIYRT |
CCCCEEEECC C CCCCEEECCC |
3.92% |
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