UniprotKB/SwissProt ID: Q91VC4 (Q91VC4)
Gene Name:
Plvap
Organism: Mus musculus (Mouse)
Function: Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Membrane, caveola. Cytoplasm, perinuclear region
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