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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Intraflagellar transport protein 81 homolog

UniprotKB/SwissProt ID: Q8WYA0 (Q8WYA0)

Gene Name: IFT81

Organism: Homo sapiens (Human)

Function: Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region (PubMed:23990561). Required for ciliogenesis (PubMed:23990561, PubMed:27666822). Required for proper regulation of SHH signaling (PubMed:27666822). Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell projection, cilium. Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029600 IFT81
IPR041146 IFT81_CH
IPR043016 IFT81_N_sf

The S-nitrosylation sites of Q8WYA0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 525 RQKYQELTQE C DEKKSQYDSC