Protein Name:
Transcriptional repressor p66-beta
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UniprotKB/SwissProt ID: Q8WXI9 (Q8WXI9)
Gene Name:
GATAD2B
Organism: Homo sapiens (Human)
Function: Transcriptional repressor (PubMed:12183469, PubMed:16415179). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:28977666). Enhances MBD2-mediated repression (PubMed:12183469, PubMed:16415179). Efficient repression requires the presence of GATAD2A (PubMed:16415179). Targets MBD3 to discrete loci in the nucleus (PubMed:11756549). May play a role in synapse development (PubMed:23644463)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus speckle. Nucleus. Chromosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8WXI9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
308 |
YQPQSSSSVP C QRTTSSAIYM |
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| 2 |
423 |
LRVEPFVCAQ C RTDFTPHWKQ |
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| 3 |
441 |
WKQEKNGKIL C EQCMTSNQKK |
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