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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: U4/U6 small nuclear ribonucleoprotein Prp31

UniprotKB/SwissProt ID: Q8WWY3 (Q8WWY3)

Gene Name: PRPF31

Organism: Homo sapiens (Human)

Function: Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11867543, PubMed:20118938, PubMed:28781166). Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:11867543)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus speckle. Nucleus, Cajal body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR042239 Nop_C
IPR002687 Nop_dom
IPR036070 Nop_dom_sf
IPR012976 NOSIC
IPR027105 Prp31
IPR019175 Prp31_C

The S-nitrosylation sites of Q8WWY3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 191 EEELERLEEA C DMALELNASK   
2 247 GLTNLSKMPA C NIMLLGAQRK   
3 299 RKAARLVAAK C TLAARVDSFH