Protein Name:
Fibroblast growth factor receptor substrate 2
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UniprotKB/SwissProt ID: Q8WU20 (Q8WU20)
Gene Name:
FRS2
Organism: Homo sapiens (Human)
Function: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endomembrane system
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Graphical Visualization of S-nitrosylation Sites:
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