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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ribonuclease TUDOR 1

UniprotKB/SwissProt ID: Q8VZG7 (Q8VZG7)

Gene Name: TSN1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress (PubMed:25736060). Essential for the integrity and function of cytoplasmic messenger ribonucleoprotein (mRNP) complexes called stress granules (SGs) and processing bodies (PBs), sites of post-transcriptional gene regulation during stress (e.g. salt and heat) (PubMed:25736060). Involved in gibberellic acid (GA) biosynthesis (PubMed:25205572). Essential for stress tolerance, probably by regulating mRNAs entering the secretory pathway (PubMed:20484005). Component of stress granules (SGs) that regulates growth under salt stress by modulating levels of GA20OX3 mRNA. Binds GA20OX3 mRNA (PubMed:25205572). May inhibit the degradation of mRNAs involved in stress adaptation (PubMed:26237081)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasmic granule. Cytoplasm, perinuclear region. Endoplasmic reticulum

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016685 Silence_cplx_Nase-comp_TudorSN
IPR035437 SNase_OB-fold_sf
IPR016071 Staphylococal_nuclease_OB-fold
IPR002999 Tudor
IPR047395 Tudor_AtTudor1-like

The S-nitrosylation sites of Q8VZG7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 854 VSAAPGLAQL C RLAYIKVPSL