Protein Name:
Filamin-C
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UniprotKB/SwissProt ID: Q8VHX6 (Q8VHX6)
Gene Name:
Flnc
Organism: Mus musculus (Mouse)
Function: Muscle-specific filamin, which plays a central role in sarcomere assembly and organization (By similarity). Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events (PubMed:16914736)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8VHX6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1104 |
GGLGLTVEGP C EAKIECQDNG |
CCCCCCCCCC C CCCCCCCCCC |
13.44% |
|
| 2 |
1349 |
SPFRVGVTEG C DPTRVRAFGP |
CCCCCCCCCC C CCCCCCCCCC |
4.63% |
20925432
|
| 3 |
1470 |
ARVPQTFTVD C SQAGRAPLQV |
CCCCCCCCCC C CCCCCCCCCC |
2.56% |
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| 4 |
1992 |
IRAPSGNEEP C LLKRLPNRHI |
CCCCCCCCCC C CCCCCCCCCC |
8.65% |
20925432
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| 5 |
2102 |
MEDGTCKVTY C PTEPGTYIIN |
CCCCCCCCCC C CCCCCCCCCC |
2.16% |
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| 6 |
2370 |
IAFEDRKDGS C GVSYVVQEPG |
CCCCCCCCCC C CCCCCCCCCC |
8.36% |
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| 7 |
2553 |
IDGPSKVQLD C RECPEGHVVT |
CCCCCCCCCC C CCCCCCCCCC |
5.54% |
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| 8 |
2556 |
PSKVQLDCRE C PEGHVVTYTP |
CCCCCCCCCC C CCCCCCCCCC |
1.6% |
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| 9 |
2661 |
VGQKNSFTVD C SKAGTNMMMV |
CCCCCCCCCC C CCCCCCCCCC |
3.8% |
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| 10 |
473 |
SPFPVHVAEA C NPNACRASGR |
CCCCCCCCCC C CCCCCCCCCC |
7% |
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| 11 |
619 |
IEGPSQAKIE C DDKGDGSCDV |
CCCCCCCCCC C CCCCCCCCCC |
10.51% |
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| 12 |
627 |
IECDDKGDGS C DVRYWPTEPG |
CCCCCCCCCC C CCCCCCCCCC |
7.39% |
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| 13 |
713 |
LKLYAQDADG C PIDIKVIPNG |
CCCCCCCCCC C CCCCCCCCCC |
2.48% |
21278135
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| 14 |
729 |
VIPNGDGTFR C SYVPTKPIKH |
CCCCCCCCCC C CCCCCCCCCC |
2.76% |
20925432
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