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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin filament-associated protein 1

UniprotKB/SwissProt ID: Q8VH46 (Q8VH46)

Gene Name: Afap1

Organism: Rattus norvegicus (Rat)

Function: Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton, stress fiber

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR030113 AFAP
IPR011993 PH-like_dom_sf
IPR001849 PH_domain

The S-nitrosylation sites of Q8VH46

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 472 NVIQTAKQTF C FMNRRAVSTS   
2 685 RTLENSPISS C DTSDAEGPLP   
3 714 KSQPSSSSSP C RGHVLQKARE