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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: SH3-containing GRB2-like protein 3-interacting protein 1

UniprotKB/SwissProt ID: Q8VD37 (Q8VD37)

Gene Name: Sgip1

Organism: Mus musculus (Mouse)

Function: May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane, clathrin-coated pit

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036168 AP2_Mu_C_sf
IPR028565 MHD
IPR018808 Muniscin_C
IPR037984 SGIP1_MHD

The S-nitrosylation sites of Q8VD37

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 402 YLETLSSPKE C GLGQRATPPP