Protein Name:
Delta(24)-sterol reductase
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UniprotKB/SwissProt ID: Q8VCH6 (Q8VCH6)
Gene Name:
Dhcr24
Organism: Mus musculus (Mouse)
Function: Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:26114596). In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Golgi apparatus membrane
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Graphical Visualization of S-nitrosylation Sites:
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