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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 3-ketoacyl-CoA thiolase B, peroxisomal

UniprotKB/SwissProt ID: Q8VCH0 (Q8VCH0)

Gene Name: Acaa1b

Organism: Mus musculus (Mouse)

Function: Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs) (Probable). Plays an important role in fatty acid peroxisomal beta-oxidation (Probable). Catalyzes the cleavage of short, medium, long, and very long straight chain 3-oxoacyl-CoAs (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002155 Thiolase
IPR016039 Thiolase-like
IPR050215 Thiolase-like_sf_Thiolase
IPR020615 Thiolase_acyl_enz_int_AS
IPR020610 Thiolase_AS
IPR020617 Thiolase_C
IPR020613 Thiolase_CS
IPR020616 Thiolase_N

The S-nitrosylation sites of Q8VCH0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 123 TVPLSTVNRQ C SSGLQAVANI  CCCHHHHHHH H CCCCCCCCHH  2.93% 22178444
2 177 RLLENEKARD C LIPMGITSEN  CCCHHHHHHH H CCCCCCCCHH  2.86% 22178444
3 218 QKAASAQSRG C FHAEIVPVTT  CCCHHHHHHH H CCCCCCCCHH  1.88% 22178444
4 381 GAIALGHPLG C TGARQVVTLL  CCCHHHHHHH H CCCCCCCCHH  4.12% 22178444