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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytochrome c oxidase assembly protein COX18, mitochondrial

UniprotKB/SwissProt ID: Q8VC74 (Q8VC74)

Gene Name: Cox18

Organism: Mus musculus (Mouse)

Function: Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2. Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001708 YidC/ALB3/OXA1/COX18
IPR028055 YidC/Oxa/ALB_C

The S-nitrosylation sites of Q8VC74

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 130 AKRLNQEVAV C ARQFGWSKRV  CCCHHHHHHH H CCCEECCCCC  1.54% 21278135