UniprotKB/SwissProt ID: Q8TF72 (Q8TF72)
Gene Name:
SHROOM3
Organism: Homo sapiens (Human)
Function: Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers (By similarity). Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, adherens junction. Cytoplasm, cytoskeleton. Apical cell membrane
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