UniprotKB/SwissProt ID: Q8TF66 (Q8TF66)
Gene Name:
LRRC15
Organism: Homo sapiens (Human)
Function: (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein (PubMed:36228039, PubMed:36735681, PubMed:36757924). Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells (PubMed:36228039, PubMed:36757924)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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