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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rap guanine nucleotide exchange factor 6
UniprotKB/SwissProt ID: Q8TEU7 (Q8TEU7)

Gene Name: RAPGEF6

Organism: Homo sapiens (Human)

Function: Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000595 cNMP-bd_dom
IPR018490 cNMP-bd_dom_sf
IPR001478 PDZ
IPR036034 PDZ_sf
IPR000159 RA_dom
IPR000651 Ras-like_Gua-exchang_fac_N
IPR023578 Ras_GEF_dom_sf
IPR001895 RASGEF_cat_dom
IPR036964 RASGEF_cat_dom_sf
IPR014710 RmlC-like_jellyroll
The S-nitrosylation sites of Q8TEU7
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1293 SMSAALQDER C SSQALAVPES   
2 1561 PASLSSNLVA C VPSKIVTQPQ   
3 840 LKNNMETETL C SDEDAQELVK