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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein phosphatase Slingshot homolog 3

UniprotKB/SwissProt ID: Q8TE77 (Q8TE77)

Gene Name: SSH3

Organism: Homo sapiens (Human)

Function: Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR014876 DEK_C
IPR000340 Dual-sp_phosphatase_cat-dom
IPR043587 Phosphatase_SSH-like
IPR029021 Prot-tyrosine_phosphatase-like
IPR043588 SSH-N
IPR016130 Tyr_Pase_AS
IPR000387 Tyr_Pase_dom
IPR020422 TYR_PHOSPHATASE_DUAL_dom

The S-nitrosylation sites of Q8TE77

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 634 QGQGQGQGEP C ISSTPRFRKV