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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: tRNA methyltransferase 10 homolog A

UniprotKB/SwissProt ID: Q8TBZ6 (Q8TBZ6)

Gene Name: TRMT10A

Organism: Homo sapiens (Human)

Function: S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs (PubMed:23042678, PubMed:25053765). Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs (PubMed:23042678)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR028564 MT_TRM10-typ
IPR038459 MT_TRM10-typ_sf
IPR016653 TRM10/TRM10A
IPR007356 tRNA_m1G_MeTrfase_euk
IPR016009 tRNA_MeTrfase_TRMD/TRM10

The S-nitrosylation sites of Q8TBZ6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 285 RKGAVPTDKA C ESASHDNQSV