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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Poly(U)-binding-splicing factor hfp

UniprotKB/SwissProt ID: Q8T6B9 (Q8T6B9)

Gene Name: hfp

Organism: Drosophila melanogaster (Fruit fly)

Function: Splicing factor that regulates oogenesis and controls both mitosis and mRNA localization in the germline by regulating mRNA splicing of a subset of genes within the ovary (PubMed:11879639). Probably acts by regulating the alternative splice site selection of the otu transcript (PubMed:11879639). Also regulates the alternative splicing of eIF4E1 and grk, while it is not involved in the splicing of par-1, sqd or psq (PubMed:11879639). Involved in the alternative splicing of the bicistronic pre-mRNA encoding Kdm3 and CG8176; required for the efficient production of mRNA encoding Kdm3 and Kdm3-mediated regulation of rhino-dependent piRNA production (PubMed:37027460)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR006532 PUF60-like
IPR051974 PUF60_regulator
IPR034209 PUF60_RRM1
IPR034211 PUF60_RRM2
IPR034212 PUF60_RRM3
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk