Protein Name:
Cytokine-like nuclear factor N-PAC
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UniprotKB/SwissProt ID: Q8T079 (Q8T079)
Gene Name:
Ndf
Organism: Drosophila melanogaster (Fruit fly)
Function: Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation and colocalizes with a subset of trimethylated 'Lys-36' histone H3 (H3K36me3)-enriched regions (PubMed:23295261, PubMed:29759984). Binds DNA (in vitro) (PubMed:29759984). Facilitates Pol II transcription through nucleosomes (PubMed:29759984). Facilitates male-specific lethal (MSL) histone acetyltransferase complex targeting to active genes on the X chromosome (PubMed:23295261). Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by nej (PubMed:29759984). May have oxidoreductase activity (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Chromosome
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Graphical Visualization of S-nitrosylation Sites:
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