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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: U4/U6 small nuclear ribonucleoprotein Prp31 homolog

UniprotKB/SwissProt ID: Q8RXN6 (Q8RXN6)

Gene Name: PRP31

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (By similarity). Functions in association with STA1 and ZOP1 in spliceosome dynamics and pre-mRNA splicing. Required for transcriptional regulation and pre-mRNA splicing of cold-responsive genes, such as LTI78/RD29A, KIN2/COR6.6 or COR15A, especially under cold stress. May play a role in stress response. Involved in transcriptional gene silencing of endogenous transposable elements, independently of the RNA-directed DNA methylation (RdDM) pathway. Seems not to participate in the small RNA biogenesis of the RdDM pathway (PubMed:25684655)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus, Cajal body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR042239 Nop_C
IPR002687 Nop_dom
IPR036070 Nop_dom_sf
IPR012976 NOSIC
IPR027105 Prp31
IPR019175 Prp31_C

The S-nitrosylation sites of Q8RXN6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 140 SLVHHPIDYA C VVKKIGNETD